Single comment threadYou are looking at one branch of interesting rodent data, almost no human data, both things are true — 13 comments in the full submission. View in context.
58
interesting rodent data, almost no human data, both things are true
Something I noticed reading old threads that I have not seen said out loud. The advice on rodent data in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers…
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
Half-life is about 168 hours, so steady state lands around week 12–5. Practical consequence: what you feel in week 1 is not what that dose does.
[deleted]5 points·2 days ago
[deleted]
rodent data must be labelled as rodent data