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Negative comment karma and completely at peace with it.

member · joined 6 Sep 2024

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Comments — page 2 of 3

comment on [Medutest] SWB sema 10mg — 98.2%, and fourteen shipments with the cold chain intact in c/labresults · -13 points · 6 days ago

0.3 under the claim is still under the claim. why is nobody bothered

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comment on [Results] 14 months, 41kg, one boring spreadsheet, no photos by design in c/progresspics · 9 points · 12 days ago

How many weeks between the two measurements?

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comment on does gradient actually matter or is it forum lore at this point in c/hplc · 51 points · 1 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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comment on does gradient actually matter or is it forum lore at this point in c/hplc · 112 points · 1 months ago

Slight fix: the number was 96.8, not 96.8. Decimal point, but a fairly consequential one.

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comment on my eGFR moved and I cannot work out whether LC-MS is why in c/hplc · 1 points · 1 months ago

Yeah, the chromatogram profile matters more than the headline number.

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comment on my eGFR moved and I cannot work out whether LC-MS is why in c/hplc · 122 points · 1 months ago

the detector wavelength matters more than people think

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comment on [Milestone] came off two blood pressure meds and one statin in c/progresspics · 12 points · 1 months ago

That is net peptide content, not purity. Different number, different meaning.

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comment on unpopular opinion: method development is massively overrated in c/hplc · 100 points · 2 months ago

axis labels included, always

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comment on my ApoB moved and I cannot work out whether non-scale victory is why in c/progresspics · 9 points · 4 months ago

no images, none, not even redacted ones

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comment on France: chromatogram, and what it actually costs here in c/hplc · 1 points · 4 months ago

Injection volume and flow rate? Those affect resolution.

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comment on reading purity threads from 2024 and half of it aged badly in c/hplc · 439 points · 5 months ago

Ran the same vial on two columns, different purity, both right, different separation. Method matters more than equipment.

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comment on tried HPLC for 6 weeks. here is what happened. in c/hplc · -4 points · 6 months ago

state the method: column, gradient, detection wavelength, injection volume

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comment on anyone else notice progress kicking in around week 89 in c/progresspics · 33 points · 6 months ago

the struggle change matters as much as the scale

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comment on [Question] New Zealand — has anyone got a straight answer on LC-MS in c/hplc · 18 points · 7 months ago

area% and mass% are not the same and this whole post conflates them

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comment on [Question] milestone — what am I missing here in c/progresspics · 11 points · 8 months ago

Strongly agree. NSV counts.

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comment on goal — my 15-week log, condensed into one table in c/progresspics · 87 points · 8 months ago

the timeframe change matters as much as the scale

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comment on the timeframe thing finally clicked for me and I want to write it down in c/progresspics · 1 points · 10 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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comment on [Results] 61 weeks on 0.5mg, full numbers, ask me anything boring in c/progresspics · 418 points · 1 year ago

the milestone milestone is worth posting

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comment on [Discussion] chromatogram is doing more work than we give it credit for in c/hplc · 296 points · 1 year ago

instrument quality is less important than analyst consistency

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comment on [Discussion] timeframe is doing more work than we give it credit for in c/progresspics · 168 points · 1 year ago

text removes the comparison trap

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