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c/glp1science·submitted 7 days ago by u/sig_figs_sam

[Paper] receptor distribution and why the GI effects were predictable

Paperbranch of 5 comments

Trying to settle this properly because the thread from last year went in circles. The claim: gastric emptying matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 14 months without either producing anything. What would actually settle it is 21 people measuring…

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5 comments, started 6 days ago
u/karma_irrelevant10 points·6 days ago
good post. terrible flair.
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u/titration_marshalmod · c/semaglutide2 points·6 days ago

This is correct. Rodent data is investigational, not predictive.

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u/yusuf_ramos1 point·5 days ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/ferran_dahlberg1 point·5 days ago

mechanistic speculation is welcome if flaired as speculation

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u/ismael_eriksen1 point·5 days ago

Yeah, the incretin mechanism is doing the work here.

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