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Single comment threadYou are looking at one branch of half-life is 168 hours. that is why your injection day barely matters. — 16 comments in the full submission. View in context.
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c/glp1science·submitted 5 days ago by u/ismael_chukwu

half-life is 168 hours. that is why your injection day barely matters.

Discussionbranch of 5 comments

Quick one. Canada here. gastric emptying works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 10 weeks and cost roughly what I expected. The admin was worse…

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5 comments, started 5 days ago
u/nora_lundgren8 points·5 days ago

gastric emptying is real and explains most early the food-noise thing

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u/hedda_adeyemi4 points·4 days ago

Stomach physiology changed when I moved up to 7.5mg. Gastric emptying lag is the whole story.

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u/vikram_mbeki3 points·4 days ago

Yeah, the incretin mechanism is doing the work here.

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u/rafael_ostergaard2 points·4 days ago

cite the paper: journal, year, first author, links optional

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u/ismael_chukwuOP-14 points·4 days ago

glucagon-receptor contribution is gastric emptying for dual and triple agonism

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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