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c/glp1science·submitted 1 year ago by u/lina_ndiaye

[Results] 66 weeks on 5mg, full numbers, ask me anything boring

Explainerbranch of 9 comments

Been lurking in c/researchpeptides for about 7 months and finally have something worth posting. Short version: week 58, 10mg, and pharmacology is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 23 threads, and the answers split roughly down the middle. What I actually want…

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9 comments, started 1 year ago
u/camila_lindqvist580 points·1 year ago
this should be in the wiki
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u/trialwatch_theotrial nerd328 points·1 year ago

Half-life is about 168 hours, so steady state lands around week 2–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/ferran_dahlberg117 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/trialwatch_theotrial nerd81 points·1 year ago

Yeah, the incretin mechanism is doing the work here.

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u/marisol_kravchenko31 points·1 year ago

amylin is not GLP-1, posts conflating them get corrected

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u/lurker_for_years36 points·1 year ago

the half-life is receptor, affects steady state timing

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u/isabela_nilsen52 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/piotr_grimaldi264 points·1 year ago

do not extrapolate rodent data to human dosing without saying so

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u/employer_carveout117 points·1 year ago

Which paper are you quoting?

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