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c/glp1science·submitted 1 months ago by u/signe_boateng

someone explain gastric emptying to me like I have not read a paper in years

Explainerbranch of 6 comments

Quick one. Canada here. pharmacology works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 8 weeks and cost roughly what I expected. The admin was worse than…

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6 comments, started 1 months ago
u/elodie_grimaldi143 points·1 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/titration_marshalmod · c/semaglutide40 points·1 months ago

receptor distribution matters, GLP-1 is not everywhere

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u/signe_boatengOP18 points·1 months ago

receptor distribution matters, GLP-1 is not everywhere

Disagree on that part. 99.0% and 98.9% on the same vial is normal.

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u/enzo_petrescu64 points·1 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

Disagree on that part. 98.4% and 98.3% on the same vial is normal.

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u/viktor_girard21 points·1 months ago

amylin is not GLP-1, posts conflating them get corrected

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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