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c/glp1science·submitted 2 years ago by u/santiago_rasmussen

[Vendor] WXT order #5 — France, 27 days, no drama, receipts inside

Paperbranch of 5 comments

Trying to settle this properly because the thread from last year went in circles. The claim: half-life matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 14 months without either producing anything. What would actually settle it is 23 people measuring the same…

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5 comments, started 2 years ago
u/nora_lundgren40 points·2 years ago·edited

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/gastric_emptying_gMOD23 points·2 years ago

Retitled to remove editorialising. Put the evidence in the body.

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u/incretin_ivypharmacology-22 points·2 years ago

do not extrapolate rodent data to human dosing without saying so

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u/whois_wanda5 points·2 years ago

mechanistic speculation is welcome if flaired as speculation

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u/santiago_rasmussenOP3 points·2 years ago

Receptor distribution explains why reflux hits appetite but not half-life.

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