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c/glp1science·submitted 2 years ago by u/signe_boateng

gastric emptying — my 18-week log, condensed into one table

Discussionbranch of 4 comments

Quick one. Canada here. appetite works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 22 weeks and cost roughly what I expected. The admin was worse than the…

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4 comments, started 2 years ago
u/yusuf_ramos199 points·2 years ago

Strongly agree. Central appetite is real but people overstate it.

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u/slow_logbook0 points·2 years ago

Strongly agree.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/whois_wanda1 point·2 years ago

glucagon-receptor contribution is receptor for dual and triple agonism

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u/incretin_ivypharmacology-22 points·2 years ago

Yeah, the incretin mechanism is doing the work here.

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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