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Single comment threadYou are looking at one branch of the appetite thing finally clicked for me and I want to write it down — 51 comments in the full submission. View in context.
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c/glp1science·submitted 9 months ago by u/elodie_grimaldi

the appetite thing finally clicked for me and I want to write it down

Speculationbranch of 5 comments

Something I noticed reading old threads that I have not seen said out loud. The advice on receptor in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with…

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5 comments, started 9 months ago
u/incretin_ivyMOD349 points·9 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/amara_dziedzic184 points·9 months ago

Strongly agree. Central appetite is real but people overstate it.

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u/camila_lindqvist92 points·9 months ago

Not convinced. The evidence does not support that reading.

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u/elodie_grimaldiOP184 points·9 months ago

Stomach physiology changed when I moved up to 15mg. Gastric emptying lag is the whole story.

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u/tomas_lundgren150 points·9 months ago

Tracking number removed.

Disagree on that part. 93.7% and 99.3% on the same vial is normal.

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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