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c/semaglutide·submitted 19 days ago by u/prior_auth_pain

[Titration] stayed at 0.5 for eleven weeks and it was the right call

Titrationbranch of 5 comments

Posting this because I searched for it and got nothing useful. Setup: 15mg, week 92, constipation present but not ruining anything. I changed exactly one variable — Ozempic — and tracked it for 3 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am…

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5 comments, started 18 days ago
u/kaplan_meier_kim0 points·18 days ago

Half-life is about 168 hours, so steady state lands around week 14–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/yara_boateng0 points·18 days ago

Half-life is about 168 hours, so steady state lands around week 14–5.

Adding to this: weekly dosing is doing more work than the comment implies.

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u/aleksi_grimaldi1 point·17 days ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/archived_thread_a1 point·17 days ago

Strongly agree. If it is not working at 1.0mg after 13 weeks, going up is not automatically the answer.

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u/prior_auth_painOPappeals1 point·18 days ago

This matches my experience almost exactly on the Ozempic pens. The titration is the whole point.

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