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c/semaglutide·posted 1 year ago by u/alcohol_aversion

[Vendor] KP vs BCH on the same compound, same month, one test each

PSA Clean Column ×1 Slow Clap ×3 Receipts ×2

I have had 18 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 4 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 96.8% against a claimed 97.2%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

12,576 up / 646 down95% upvoted41 commentsid 1cnavm12 Apr 2025

41 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/iman_castellanos2.4k points·1 year ago

This matches my experience almost exactly on the Ozempic pens. The titration is the whole point.

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u/stubborn_batchlist_only1.9k points·1 year ago

Slight fix: the number was 96.8, not 96.8. Decimal point, but a fairly consequential one.

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u/ewan_tulloch1k points·1 year ago

Not to be pedantic but weekly dosing and semaglutide are being used interchangeably and they are not interchangeable in real life.

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u/quiet_moderatormod0 points·1 year ago

This matches my experience almost exactly on the Ozempic pens.

Adding to this: Ozempic is doing more work than the comment implies.

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u/adnan_karlsen1 point·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/salma_vasquez0 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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[deleted]1 point·1 year ago

[deleted]

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u/customs_seizure_sid1.1k points·1 year ago

Kept a public log for 22 weeks. The comments are what kept it going, honestly. Accountability from strangers works.

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u/alcohol_aversionOP605 points·1 year ago

Strongly agree. If it is not working at 5mg after 33 weeks, going up is not automatically the answer.

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u/vikram_mbeki1.1k points·1 year ago

This is what I tell everyone in c/newbiequestions and they never believe me until week 39.

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u/units_not_mgMOD780 points·1 year ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/zeynep_weiss541 points·1 year ago

my triglycerides moved before the scale did and i nearly missed it

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u/arne_restrepo452 points·1 year ago

Slight fix: the number was 98.7, not 98.9. Decimal point, but a fairly consequential one.

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u/greta_lokken305 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/prior_auth_painappeals156 points·1 year ago

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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u/alcohol_aversionOP71 points·1 year ago

stalled at 1.0mg, went up, and regretted it, the stall would have broken anyway

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u/kenji_demir69 points·1 year ago·edited

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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u/hassan_ostergaard265 points·1 year ago

week 64 and i am still not at maintenance, do not rush the ladder

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u/ahmed_abubakar142 points·1 year ago

okay but what dose of sema are you on

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u/test_it_yourselfvetting113 points·1 year ago

my hs-CRP moved before the scale did and i nearly missed it

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u/units_not_mgsyringe math-15 points·1 year ago

pens are overpriced, research vials are research grade, same molecule different price

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u/zeynep_zielinski95 points·1 year ago

week 64 and i am still not at maintenance, do not rush the ladder

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/alcohol_aversionOP68 points·1 year ago

titration speed is titration plus side effects, period

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u/zeynep_weiss252 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/two_mil_or_one612 points·1 year ago·edited
post the spreadsheet
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u/hassan_ostergaard750 points·1 year ago

okay but what dose of sema are you on

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u/chidi_demir271 points·1 year ago

Not to be pedantic but Wegovy and weekly dosing are being used interchangeably and they are not interchangeable in real life.

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u/meta_analysis_mo337 points·1 year ago

What was the method? "HPLC" is a technique, not a method.

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u/kenji_demir500 points·1 year ago·edited

week 95 and i am still not at maintenance, do not rush the ladder

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u/ewan_tulloch365 points·1 year ago

Yeah, 18 weeks on 2.5mg, same pattern, same timing.

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Everything semaglutide: branded pens, compounded vials, oral formulations and the research-grade material people reconstitute themselves. Titration schedules, side-effect management, plateau troubleshooting and long-term maintenance. Dose questions are welcome; "what dose should I take" answers are not, because nobody here is your prescriber.

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