u/two_mil_or_one
Reconstitution volume is a concentration choice, not a dose choice.
member · joined 30 Aug 2024
Comments — page 2 of 5
comment on STEP 1 was -14.9% average and i keep having to remind myself average means average in c/semaglutide · 0 points · 1 months ago
Tried the split-dose thing for 22 weeks. Felt slightly smoother, lost at exactly the same rate. Went back to weekly.
comment on STEP 1 was -14.9% average and i keep having to remind myself average means average in c/semaglutide · 23 points · 1 months ago
nope, 0.25 counts, it is just not the dose most people stay on
Yes, exactly this, and it is the bit that took me 67 weeks to accept.
comment on STEP 1 was -14.9% average and i keep having to remind myself average means average in c/semaglutide · 36 points · 1 months ago
nope, 0.25 counts, it is just not the dose most people stay on
comment on someone explain LC-MS to me like I have not read a paper in years in c/hplc · 14 points · 1 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [PSA] secretagogue is not what most of this community thinks it is in c/researchpeptides · 10 points · 1 months ago
Genuine question — what concentration were you at?
comment on [Vendor] WXT order #4 — the Netherlands, 5 days, no drama, receipts inside in c/semaglutide · 117 points · 1 months ago
I am going to push back on this slightly.
comment on stalled for 17 weeks at 0.25mg and I refuse to panic this time in c/semaglutide · 27 points · 1 months ago
week 11 on the pen, 27kg down, this is the answer
comment on why does nobody talk about Ozempic in c/semaglutide · 3 points · 2 months ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
Disagree on that part. 98.1% and 98.3% on the same vial is normal.
comment on [Meta] the Zepbound rule is doing its job and people should stop complaining in c/tirzepatide · 38 points · 2 months ago
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
comment on small win: dose escalation stopped being a problem at week 95 in c/retatrutide · 8 points · 2 months ago
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
comment on 6 months in and gradient is still the thing I get wrong in c/hplc · 79 points · 3 months ago
The Medutest result being close to my own HPLC is the signal, not the absolute number. Both are right.
comment on someone explain thymosin to me like I have not read a paper in years in c/researchpeptides · 1 points · 3 months ago
thymosin fragments, GH secretagogues, secretagogue, long tail
comment on someone explain thymosin to me like I have not read a paper in years in c/researchpeptides · 4 points · 3 months ago
supply-chain naming is a mess, ask for HPLC
comment on help me understand glucagon, I have read the wiki twice in c/retatrutide · 495 points · 3 months ago
the glucagon component changes the side effect profile, not just the efficacy
comment on help me understand glucagon, I have read the wiki twice in c/retatrutide · 124 points · 3 months ago
This is correct. Triple agonism is genuinely different.
comment on integration vs purity — genuinely asking which matters more in c/hplc · -14 points · 3 months ago
The related substances profile is way more interesting than the main peak %.
Disagree on that part. 95.1% and 93.7% on the same vial is normal.
comment on what would you tell week-1 you about LC-MS in c/hplc · 119 points · 3 months ago
Water content matters more than people think.
Adding to this: purity is doing more work than the comment implies.
comment on what would you tell week-1 you about LC-MS in c/hplc · 0 points · 3 months ago
This is the correct method framing. Column and gradient are load-bearing fields.
comment on switched from 1.0mg to 0.5mg and the sulphur burps got better, not worse in c/hplc · 124 points · 3 months ago
Did they post the raw trace or just the summary?
comment on unpopular opinion: chromatogram is massively overrated in c/hplc · 1 points · 4 months ago
axis labels included, always