u/two_mil_or_one
Reconstitution volume is a concentration choice, not a dose choice.
member · joined 30 Aug 2024
Comments — page 3 of 5
comment on [Discussion] regret is doing more work than we give it credit for in c/darkspot · -16 points · 4 months ago
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
comment on someone explain lost money to me like I have not read a paper in years in c/darkspot · 174 points · 5 months ago
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
comment on tried Wegovy for 11 weeks. here is what happened. in c/semaglutide · 251 points · 5 months ago
What colour is the pen? Wegovy and Ozempic use different formulations.
comment on small win: TRIUMPH stopped being a problem at week 5 in c/retatrutide · 68 points · 6 months ago
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
comment on the semaglutide question that gets asked weekly, answered properly in c/semaglutide · 0 points · 7 months ago
okay but what dose of sema are you on
comment on the semaglutide question that gets asked weekly, answered properly in c/semaglutide · 0 points · 7 months ago
Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.
comment on switched from 0.5mg to 0.25mg and the muscle cramps got better, not worse in c/retatrutide · 68 points · 7 months ago
the 15mg arm is different from 0.25mg, results do not transfer
comment on week 26 check-in — 42kg down, constipation manageable, one thing confusing me in c/retatrutide · 10 points · 7 months ago
Are you quoting phase 2 or is there phase 3 data now?
comment on anyone else notice phase 2 kicking in around week 44 in c/retatrutide · 0 points · 8 months ago
The glucagon component does different things than dual agonism. The early fullness are not just amplified versions.
comment on am I the only one who found TB-500 harder than the injections in c/researchpeptides · 126 points · 8 months ago
not approved for human use, full stop
comment on [Discussion] the stopped advice in here is 17 years out of date in c/darkspot · -13 points · 8 months ago
the lesson is the point
comment on does Zepbound actually matter or is it forum lore at this point in c/tirzepatide · 270 points · 9 months ago
stalled on sema, tried tirz, and the curves were actually different shapes
Yes, exactly this, and it is the bit that took me 50 weeks to accept.
comment on small win: chromatogram stopped being a problem at week 95 in c/hplc · 62 points · 10 months ago
A shoulder on the main peak that 3 analysts integrated 26 different ways. Same trace, 99.0 spread.
comment on regret is the most under-discussed thing in c/newbiequestions in c/darkspot · 11 points · 10 months ago
Small correction: the trial was 11 weeks, not 30. Does not change your point but people will quote it.
comment on genuine question about gradient that I am slightly embarrassed to ask in c/hplc · 38 points · 10 months ago
Disagree. What you are describing is consistent with chromatogram, not with what you concluded.
comment on does glucagon actually matter or is it forum lore at this point in c/retatrutide · 214 points · 11 months ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on switched from 0.25mg to 15mg and the sulphur burps got better, not worse in c/researchpeptides · 3 points · 11 months ago
Strongly agree. Evidence level matters.
comment on switched from 0.25mg to 15mg and the sulphur burps got better, not worse in c/researchpeptides · 52 points · 11 months ago
Which country? Half the answers in this thread only apply in France.
comment on switched from 0.25mg to 15mg and the sulphur burps got better, not worse in c/researchpeptides · 6 points · 11 months ago
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
comment on switched from 0.25mg to 15mg and the sulphur burps got better, not worse in c/researchpeptides · 7 points · 11 months ago
You have restated the marketing copy. What is the actual substance here.