week 26 check-in — 42kg down, constipation manageable, one thing confusing me
Been lurking in c/sideeffects for about 12 months and finally have something worth posting.
Short version: week 40, 10mg, and triple agonist is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 17 threads, and the answers split roughly down the middle.
What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 46.
best — the order this archive was captured in
the dosing is steep, the injection-site soreness reports are real, and nobody knows the human safety yet
Are you quoting phase 2 or is there phase 3 data now?
the dosing is steep, the muscle cramps reports are real, and nobody knows the human safety yet
Respectfully this is a sample of one presented as a finding.
the weight curves are unusually steep, which makes predicting individual response harder
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
triple agonism is glucagon, do not generalise
Strongly agree. Heart rate escalation needs the actual data, not impressions.
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
Removed a chain here. The rule is one line long and it is not negotiable.
Are you quoting phase 2 or is there phase 3 data now?
Strongly agree. Heart rate escalation needs the actual data, not impressions.
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
Dose escalation on retatrutide is steeper and faster than on semaglutide.
Yes, exactly this, and it is the bit that took me 42 weeks to accept.
Strongly agree. Heart rate escalation needs the actual data, not impressions.
[deleted]
Small correction: the trial was 9 weeks, not 8. Does not change your point but people will quote it.
- 1Research use material only, no human-use approval anywhere. Posts must…6 comments in this branch · started by u/nikhil_lindqvist
- 2the dosing is steep, the injection-site soreness reports are real, and…5 comments in this branch · started by u/farid_molnar