[Results] 37 weeks, 16kg, and phase 2 was the hard part
Quick one. Canada here.
glucagon works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.
Specifics: the route I used took 18 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.
Happy to answer questions from anyone in the same jurisdiction.
best — the order this archive was captured in
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
Retitled to remove editorialising. Put the evidence in the body.
triple agonism is phase 2, do not generalise
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
Mechanistically the bit that matters is retatrutide. It explains most of the early profile and a decent chunk of the outcome.
This is correct. Triple agonism is genuinely different.
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the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
This is correct. Triple agonism is genuinely different.
nobody should be giving this to anyone without extensive monitoring
the glucagon component changes the side effect profile, not just the efficacy
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
the glucagon component changes the side effect profile, not just the efficacy
This is correct. Triple agonism is genuinely different.
Small correction: the trial was 18 weeks, not 26. Does not change your point but people will quote it.
This is correct. Triple agonism is genuinely different.
I am going to push back on this slightly.
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
This is correct. Triple agonism is genuinely different.
Disagree. What you are describing is consistent with retatrutide, not with what you concluded.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
- 1Inter-lab variance on this kind of assay is routinely 1–2 points. Different…9 comments in this branch · started by u/fabio_lehtinen
- 2This is correct. Triple agonism is genuinely different.7 comments in this branch · started by u/helga_vermeulen