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c/retatrutide·submitted 1 year ago by u/freya_baptista

[Results] 37 weeks, 16kg, and phase 2 was the hard part

Resultsbranch of 9 comments

Quick one. Canada here. glucagon works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 18 weeks and cost roughly what I expected. The admin was worse than the…

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9 comments, started 1 year ago
u/fabio_lehtinen0 points·1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/arne_amankwah1 point·1 year ago·edited

Mechanistically the bit that matters is retatrutide. It explains most of the early profile and a decent chunk of the outcome.

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u/incretin_ivypharmacology1 point·1 year ago

This is correct. Triple agonism is genuinely different.

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[removed]1 point·1 year ago

[removed by moderator]

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u/hassan_nilsen1 point·1 year ago

the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet

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u/lurker_for_years1 point·1 year ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/discount_math_dm1 point·1 year ago

This is correct. Triple agonism is genuinely different.

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u/freya_baptistaOP1 point·1 year ago

nobody should be giving this to anyone without extensive monitoring

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u/freya_baptistaOP1 point·1 year ago

the glucagon component changes the side effect profile, not just the efficacy

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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