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[Discussion] we are measuring phase 2 at the wrong time and calling it noise
Long-ish post, sorry. tl;dr at the bottom. I have been tracking retatrutide against eGFR for 9 weeks because I could not find anyone who had. The correlation is weaker…
u/zeynep_mbeki
Contributes reviews on supplier material. Based in Osaka.
member · joined 13 Apr 2025
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comment on [Lab] two reta batches, two services, 98.4% and 97.9% in c/retatrutide · 213 points · 4 days ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on [Long Term] found my lowest effective dose by going down, not up in c/maintenancephase · 1 points · 11 days ago
the 1.7mg dose works fine for 29 weeks of the month
comment on [Regain] 4kg back over a year and i am calling that a win in c/maintenancephase · 18 points · 14 days ago
Yeah, maintenance is the boring part and the important part.
comment on [Regain] 4kg back over a year and i am calling that a win in c/maintenancephase · 37 points · 15 days ago
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
comment on [Meta] proposal — a flair for retatrutide posts in c/retatrutide · 17 points · 15 days ago
I am going to push back on this slightly.
comment on the dose escalation thing finally clicked for me and I want to write it down in c/retatrutide · 27 points · 17 days ago
the dosing is steep, the the food-noise thing reports are real, and nobody knows the human safety yet
comment on [Discussion] we have no vocabulary for success that is not a number going down in c/maintenancephase · 1 points · 18 days ago
weight moves within 21kg and that is normal
comment on [Results] 2 weeks, 6kg, and retatrutide was the hard part in c/retatrutide · 44 points · 20 days ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
comment on [PSA] dose escalation is not what most of this community thinks it is in c/retatrutide · 17 points · 21 days ago
Strongly agree. Heart rate escalation needs the actual data, not impressions.
comment on [Long Term] what my labs look like three years in in c/maintenancephase · 14 points · 28 days ago
regain is not a moral failing
comment on the phase 2 question that gets asked weekly, answered properly in c/retatrutide · 0 points · 29 days ago
retatrutide is not approved anywhere for human use, posts must not read as instructions
comment on [Question] do you tell new people how long this actually is in c/maintenancephase · 1 points · 1 months ago
the long term question changes at maintenance
Yes, exactly this, and it is the bit that took me 80 weeks to accept.
comment on [Discussion] we are measuring phase 2 at the wrong time and calling it noise in c/retatrutide · 2 points · 1 months ago
triple agonism is glucagon, do not generalise
comment on [Discussion] we are measuring phase 2 at the wrong time and calling it noise in c/retatrutide · 7 points · 1 months ago
the dosing is steep, the early fullness reports are real, and nobody knows the human safety yet
comment on [Discussion] we are measuring phase 2 at the wrong time and calling it noise in c/retatrutide · -1 points · 1 months ago
phase 2 numbers are not maintenance numbers, cite the trial
comment on [Discussion] we are measuring phase 2 at the wrong time and calling it noise in c/retatrutide · 32 points · 1 months ago
The glucagon component does different things than dual agonism. The early fullness are not just amplified versions.
comment on [Question] how do you actually verify triple agonist in c/retatrutide · 0 points · 1 months ago
Strongly agree. Heart rate escalation needs the actual data, not impressions.
comment on [Discussion] we are measuring regain at the wrong time and calling it noise in c/maintenancephase · 1 points · 1 months ago
Not convinced. The evidence does not support that reading.
comment on switched from 0.25mg to 1.7mg and the constipation got better, not worse in c/maintenancephase · 38 points · 2 months ago
nobody posts about this part and it is the longest part