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894
c/coldchain·posted 13 days ago by u/zeynep_ndiaye

[Data] my fridge is 2.1°C at the back and 7.8°C in the door. same fridge.

Data Sourced ×4

Posting this because I searched for it and got nothing useful.

Setup: 0.5mg, week 93, constipation present but not ruining anything. I changed exactly one variable — data logger — and tracked it for 3 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

992 up / 98 down91% upvoted64 commentsid 1qkkl017 Jul 2026

64 comments

29 in this archive, depth 5

best — the order this archive was captured in

u/ireland_drugs_pay138 points·13 days ago

customs clearance often breaks the cold chain, factor that in

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u/cesar_teixeira68 points·12 days ago·edited

Which carrier and route?

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u/preservative_free_p-9 points·12 days ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/nils_ferreira1 point·12 days ago·edited

Yeah, data logger is the only acceptable proof.

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u/creatine_and_cardio1 point·11 days ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/britt_okwuosa1 point·11 days ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/certified_referenceQC67 points·11 days ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/split_dose_sceptic17 points·11 days ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/iman_castellanos15 points·11 days ago

Disagree. What you are describing is consistent with ice pack, not with what you concluded.

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u/nightowl_injector12 points·11 days ago

time-at-temperature integral is the dose, not just peak temperature

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u/zeynep_ndiayeOP5 points·10 days ago

France to France: 22 days with ERP and 17 days with HJ. Same route, different carriers, variance is real.

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u/zeynep_ndiayeOP11 points·11 days ago

Germany to Germany: 12 days with SWB and 24 days with MKM. Same route, different carriers, variance is real.

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u/chidi_abubakar4 points·10 days ago

Yeah, data logger is the only acceptable proof.

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u/usb_logger_ursula7 points·11 days ago

the logger trace is the data that matters, not the packaging promises

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u/sequence_checkerresearch peptides29 points·11 days ago

Reconstituted or dry powder?

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u/priya_guerrero9 points·10 days ago·edited

Reconstituted or dry powder?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/maren_sorensen37 points·12 days ago·edited

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/osman_brandt9 points·12 days ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

Adding to this: packaging is doing more work than the comment implies.

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u/solene_abubakar6 points·11 days ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/meera_sandvik5 points·11 days ago

Slight fix: the number was 97.2, not 97.4. Decimal point, but a fairly consequential one.

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u/britt_okwuosa1 point·11 days ago

Not convinced. The evidence does not support that reading.

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u/sterile_field_steph5 points·11 days ago

lane reports need origin, destination, carrier, and actual transit days

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u/zeynep_ndiayeOP4 points·11 days ago

Strongly agree. Peak temperature is not the whole story.

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u/vito_chowdhury3 points·11 days ago

a warm courier van is a bigger problem for a mixed vial than for dry powder

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u/kian_solberg1 point·11 days ago

Reconstituted or dry powder?

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u/adaeze_weiss31 points·12 days ago

Yeah, data logger is the only acceptable proof.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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c/coldchain rules
  1. Excursion claims need a logger trace or a photo taken at unboxing. "It felt warm" is not data.
  2. No tracking numbers, ever. They identify you and the recipient.
  3. Stability claims need a source or an explicit "this is my guess" label.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
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