u/mod_cold_room
c/coldchain mod. Fridge thermometer evangelist. Ask me about excursion tables.
moderator · mod · c/coldchain · joined 17 Apr 2024
comment on interesting rodent data, almost no human data, both things are true in c/bpc157 · 2 points · 17 hr ago
Strongly agree. Zero human controlled data.
comment on [Below Spec] 61.2% on a vial i had already been using for six weeks in c/labresults · 176 points · 1 days ago
Crossposting to c/coldchain with the author's permission. We have very little published data on real-world reconstituted degradation and this is a data point, even an accidental one.
comment on [Resolved] the QST batch dispute — vendor retested at their own cost, numbers matched, my error in c/scamalerts · 121 points · 3 days ago
It is also the second accidental data point on real-world reconstituted degradation this quarter, and there is almost none of it published. Crossposting with permission.
comment on [Failure] gel pack arrived liquid and warm in July. photos at unboxing. in c/coldchain · 289 points · 3 days ago
Correct flair. Packaging failure and product failure are different events and this community should keep counting them separately — a vendor whose packaging fails and whose product survives is telling you they have got lucky with a robust molecule, not that they have solved the problem.
Logged for the summer table.
comment on [Data] logger trace: 6 days transit, 41 hours above 8°C, powder was fine in c/coldchain · 367 points · 3 days ago
This is the reference post for the community and I am stickying it. One thing to underline because it gets missed: the pack exhausting by hour 30 is by design on a six-day lane. A gel pack is not meant to last the whole trip; it is meant to buy you the first day while the parcel is still warm from the origin.
People treat a liquid gel pack as evidence of failure. It is evidence of a finite coolant budget being spent.
comment on [Delay] two weeks in a transit hub, then delivered fine in c/intlshipping · 23 points · 3 days ago
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
comment on [Lab] three BPC vials, three vendors, purity all over the place in c/bpc157 · 0 points · 4 days ago
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
comment on reconstituted vial left out for five hours — bin it or not in c/coldchain · 132 points · 4 days ago
Leaving this up as a reference question. The powder-versus-solution distinction is the most useful single idea in this community and this thread is a clean worked example of applying it.
comment on [Lab] SSA tirz 10mg — Janoshik 99.1%, third batch in a row in c/tirzepatide · 1 points · 4 days ago
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
Yes, exactly this, and it is the bit that took me 78 weeks to accept.
comment on why is nobody talking about the SURPASS-CVOT readout in c/tirzepatide · 42 points · 5 days ago
How long at each step before you escalated?
comment on [Explainer] lyophilised powder is far more forgiving than you think in c/coldchain · 135 points · 5 days ago
Tracking number removed. It identifies both ends of a shipment.
comment on [Discussion] dose-response looked steeper than anything else in the class and that cuts both ways in c/retatrutide · 4 points · 8 days ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
comment on [PSA] never the fridge door. the door is the warmest wobbliest shelf you own in c/coldchain · 44 points · 9 days ago
Peak temperature and how long at that temperature?
comment on [Delay] customs held it 19 days and released it with no note in c/intlshipping · 8 points · 15 days ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on [Failure] vendor packed a cold box with no thermal mass. just foam and hope. in c/coldchain · 14 points · 16 days ago
Tracking number removed. It identifies both ends of a shipment.
comment on SURMOUNT-1 was -20.9% at 72 weeks. that is the number, not -30% in c/tirzepatide · 50 points · 16 days ago
the GIP side does different things than the GLP-1 side, that is the point
comment on three years of glucagon threads, summarised so you do not have to read them in c/survodutide · 34 points · 17 days ago
Stalled for 16 weeks, changed nothing, and it started moving again on week 24.
comment on [Discussion] we have no vocabulary for success that is not a number going down in c/maintenancephase · 54 points · 18 days ago
How long at maintenance?
comment on [Data] packaging quality by vendor, scored on five things, 60 shipments in c/intlshipping · 1 points · 20 days ago
This is correct. Variance is the story.
comment on domain registered eleven days ago, 400 five-star reviews. sure in c/vendorvetting · 7 points · 20 days ago
the reship rate on BCH is actually pretty consistent