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c/survodutide·posted 18 days ago by u/renzo_yildiz

three years of glucagon threads, summarised so you do not have to read them

Paper

Posting this because I searched for it and got nothing useful.

Setup: 2.5mg, week 87, constipation present but not ruining anything. I changed exactly one variable — hepatic fat — and tracked it for 15 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

301 up / 48 down86% upvoted16 commentsid 19g6ec12 Jul 2026

16 comments

9 in this archive, depth 4

best — the order this archive was captured in

u/mod_cold_roommod · c/coldchain34 points·17 days ago

Stalled for 16 weeks, changed nothing, and it started moving again on week 24.

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u/vikram_mbeki16 points·17 days ago

hepatic fat and survodutide are the story

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u/incretin_ivyMOD23 points·17 days ago

Tracking number removed. It identifies both ends of a shipment.

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u/heart_rate_bump18 points·17 days ago

hepatic fat and hepatic fat are the story

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u/cato_batista27 points·17 days ago

do not generalise from tirzepatide

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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