[Meta] proposal — a flair for survodutide posts
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking survodutide against eGFR for 21 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
Which trial arm?
the safety profile is not just tirzepatide amplified
Not convinced. The evidence does not support that reading.
glucagon co-agonism has a different safety story
You have restated the marketing copy. What is the actual substance here.
I am going to push back on this slightly.
the heart rate signal is real in the data
Sceptical. If this were true we would see it reflected in the data and we do not.
Strongly agree. The safety story is separate.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Sceptical. If this were true we would see it reflected in the data and we do not.
Strongly agree. The safety story is separate.
Strongly agree.
Yes, exactly this, and it is the bit that took me 83 weeks to accept.
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
Titration speed is a side-effect dial far more than an efficacy dial.
- 1Not convinced. The evidence does not support that reading.7 comments in this branch · started by u/sofia_danquah
- 2ask your actual doctor, not us4 comments in this branch · started by u/clara_restrepo