u/nora_oyelaran

What was the dropout rate?

phase 2 is not phase 3, smaller n and shorter trial

hormonal contraception interactions are speculative

the heart rate signal is real in the data

phase 2 is not phase 3, smaller n and shorter trial

Disagree on that part. 99.0% and 98.9% on the same vial is normal.

Disagree. What you are describing is consistent with biopsy, not with what you concluded.

Came off after 54 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

Week 77 for me and the honest summary is: 5kg down, muscle cramps manageable, and I have thought about food maybe four times today.

phase 13 data is interesting, phase 26 will be different

off-label use data is different from approved-indication data

Crossposting this to c/t2dglp1 because the people who need it are not reading this community.

Adding to this: insulin resistance is doing more work than the comment implies.

This is correct. Evidence still required.

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

rodent survodutide is investigation only

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

the GLP-1/glucagon dual is hepatic fat, different from GIP/GLP-1

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

hair-loss on contraception is real

that is the funniest sentence i have read on this site

Adding to this: fertility is doing more work than the comment implies.

What are you comparing it against though?