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c/glp1women·posted 16 days ago by u/step_therapy_s

[PCOS] my androgens moved before my weight did

PCOS Receipts ×7

Genuinely asking, not being difficult.

Everyone in c/darkspot repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 8 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

1,792 up / 1,566 down53% upvoted17 commentsid 1vmjkd14 Jul 2026

17 comments

17 in this archive, depth 4

best — the order this archive was captured in

u/blunt_coldbox_notes36 points·14 days ago

Not convinced. The evidence does not support that reading.

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u/micro_bump_mick9 points·14 days ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/ewan_zielinski0 points·14 days ago

contraception interaction claims need citation

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u/niels_roos19 points·14 days ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/low_appetite_lisa-5 points·14 days ago

Strongly agree. Cycle changes are documented.

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u/ewan_tulloch1 point·14 days ago

Yeah, insulin resistance is under-researched.

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u/step_therapy_sOP0 points·14 days ago

Strongly agree. Cycle changes are documented.

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u/lipid_panel_larrybloodwork1 point·13 days ago

cycle changes are real and under-researched

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u/step_therapy_sOP1 point·13 days ago

contraception interaction claims need citation

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u/cold_chromatogram1 point·13 days ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/idris_kimani1 point·14 days ago

Stalled for 17 weeks, changed nothing, and it started moving again on week 71.

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u/nayeli_iyer13 points·14 days ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/ravi_bergstrom3 points·13 days ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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  2. Contraception interaction claims need a citation.
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