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c/glp1women·posted 1 year ago by u/nnt_nate

Germany: contraception, and what it actually costs here

Results Long Haul ×5 Clean Column ×3 Cold Box ×3

Something I noticed reading old threads that I have not seen said out loud.

The advice on perimenopause in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

4,772 up / 442 down92% upvoted48 commentsid 4eh6dh28 Dec 2024

48 comments

24 in this archive, depth 5

best — the order this archive was captured in

u/rui_only_ro967 points·1 year ago

Strongly agree. Cycle changes are documented.

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u/bastian_moreau336 points·1 year ago

The reflux was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/forest_plot_fionastats670 points·1 year ago

Half-life is about 168 hours, so steady state lands around week 11–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/nnt_nateOP315 points·1 year ago

This is correct. PCOS is real.

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u/ferran_laurent457 points·1 year ago

the cycle tracking data matters, keep it private

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u/katrin_diallo283 points·1 year ago

the cycle tracking data matters, keep it private

Yes, exactly this, and it is the bit that took me 57 weeks to accept.

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u/honest_syringe_2025437 points·1 year ago

This is correct. PCOS is real.

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u/neha_rahimi294 points·1 year ago

Ireland here. Waited 19 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/samir_falk241 points·1 year ago

no cycle-tracking data with identifying details

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u/step_therapy_s71 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/low_appetite_lisa202 points·1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/nnt_nateOP144 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/low_appetite_lisa100 points·1 year ago

Yeah, PCOS is under-researched.

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u/blunt_coldbox_2024126 points·1 year ago

What are you comparing it against though?

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u/coa_forgery_watch29 points·1 year ago

the PCOS question is under-powered in trials

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u/blunt_coldbox_notes72 points·1 year ago

hormonal contraception interactions are speculative

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u/ferran_mensah34 points·1 year ago

hormonal contraception interactions are speculative

Adding to this: insulin resistance is doing more work than the comment implies.

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u/niels_roos66 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/low_appetite_lisa19 points·1 year ago

Slight fix: the number was 93.7, not 99.3. Decimal point, but a fairly consequential one.

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u/gentle_correctionnice about it15 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/lipid_panel_larrybloodwork10 points·1 year ago

PCOS and insulin resistance

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u/usp_appendixcompendial-28 points·1 year ago

Genuine question — what concentration were you at?

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u/katrin_diallo17 points·1 year ago

Disagree. What you are describing is consistent with insulin resistance, not with what you concluded.

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u/rina_sobczak7 points·1 year ago

Disagree.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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