u/nnt_nate
Number needed to treat, or I am not interested.
member · joined 6 May 2024
comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 154 points · 1 days ago
which makes it one of the few readouts where I do not have to demand the number needed to treat, because it is small enough to be obviously worth it.
comment on anyone actually tracked their own sides before/after switching to a split schedule in c/semaglutide · 31 points · 2 days ago
would need something like an A/B/A design, back to single dosing for a stretch and see if sides come back, to actually separate the two effects, which is a big ask to expect from self-experimentation
comment on [PSA] how to actually tell noise from a real plateau instead of guessing in c/semaglutide · 27 points · 6 days ago
would love a version of this table with actual sample sizes attached, "likely noise" vs "likely real" without an n behind it is still a bit of a vibe even if a well-reasoned one
comment on [Method] 220nm vs 214nm and what you lose at each in c/hplc · 1 points · 12 days ago
integration decision on a shoulder changes your number by half a point on its own
comment on [Win] HSA dollars changed the real cost by a third and i nearly missed it in c/insurancefights · 2 points · 17 days ago
do not suggest misrepresenting a diagnosis, that is fraud
comment on [Discussion] we have no vocabulary for success that is not a number going down in c/maintenancephase · 100 points · 18 days ago
nobody posts about this part and it is the longest part
comment on stretching to 10 days instead of 7 — anyone doing this long term in c/maintenancephase · 56 points · 23 days ago
Did you stretch the dose interval?
comment on week 26 check-in — 31kg down, muscle cramps manageable, one thing confusing me in c/bloodwork · 6 points · 28 days ago
eGFR from 2 to 3 is movement, not noise
comment on Spain: PCOS, and what it actually costs here in c/glp1women · 3 points · 1 months ago
fertility signal is there but unclear
comment on [Regain] appetite came back over about five weeks, not overnight in c/maintenancephase · 34 points · 1 months ago
Yeah, maintenance is the boring part and the important part.
comment on [PSA] integration is not what most of this community thinks it is in c/hplc · 42 points · 1 months ago
Small correction: the trial was 16 weeks, not 21. Does not change your point but people will quote it.
comment on ALT — 6 things I got wrong before I got it right in c/bloodwork · 21 points · 1 months ago
Is that fasted?
comment on [Discussion] can we stop arguing about eGFR until somebody posts a number in c/bloodwork · 1 points · 1 months ago
Is that fasted?
comment on [Discussion] can we stop arguing about eGFR until somebody posts a number in c/bloodwork · 1 points · 1 months ago
Is that fasted?
comment on what would you tell week-1 you about HPLC in c/hplc · 264 points · 2 months ago
state the method: column, gradient, detection wavelength, injection volume
comment on switched from 0.25mg to 1.7mg and the constipation got better, not worse in c/maintenancephase · 61 points · 2 months ago
the 15mg dose works fine for 78 weeks of the month
comment on genuine question about insulin resistance that I am slightly embarrassed to ask in c/glp1women · 57 points · 2 months ago
hormonal contraception interactions are speculative
comment on stalled for 10 weeks at 0.5mg and I refuse to panic this time in c/bloodwork · 8 points · 2 months ago
Not convinced. The evidence does not support that reading.
comment on [Question] copay — what am I missing here in c/insurancefights · 1 points · 2 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Question] copay — what am I missing here in c/insurancefights · 11 points · 2 months ago
say which country and which plan type