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crossposted from c/semaglutide by u/zeynep_weiss — tried semaglutide for 15 weeks. here is what happened.
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c/bloodwork·posted 1 months ago by u/mateusz_achebe

[Discussion] can we stop arguing about eGFR until somebody posts a number

Discussion

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking eGFR against triglycerides for 9 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

0 up / 0 down47% upvoted8 commentsid 15gmge19 Jun 2026

8 comments

8 in this archive, depth 3

best — the order this archive was captured in

u/greta_chukwu2 points·1 months ago·edited

eGFR from 13 to 5 is movement, not noise

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u/nnt_nate1 point·1 months ago

Is that fasted?

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u/tidy_vialdrawer_watch-16 points·1 months ago

baseline is the most important A1c measurement, you cannot collect it later

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u/lipid_panel_larrybloodwork1 point·1 months ago

Strongly agree. ALT is where you catch the liver story early.

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u/gentle_correctionMOD1 point·1 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/nnt_nate1 point·1 months ago

Is that fasted?

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u/constipation_clubside effects1 point·1 months ago

Is that fasted?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/mateusz_achebeOP1 point·1 months ago

ALT is where the fatty-liver story shows up first

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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