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c/bloodwork·posted 1 year ago by u/bac_water_bandit

week 61 check-in — 46kg down, early fullness manageable, one thing confusing me

Results Receipts ×8 Clean Column ×3 Cold Box ×3

Genuinely asking, not being difficult.

Everyone in c/t2dglp1 repeats that baseline labs is important. I believe it, but I have never seen anyone show why, and when I search I get 14 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

6,150 up / 786 down89% upvoted35 commentsid 53t2168 Feb 2025

35 comments

28 in this archive, depth 4

best — the order this archive was captured in

u/intent_to_treat433 points·1 year ago

I am going to push back on this slightly.

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u/bac_water_banditOPreconstitution305 points·1 year ago

HOMA-IR is crude but free and useful for tracking

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u/lipid_panel_larrybloodwork388 points·1 year ago

HOMA-IR is crude but free and useful for tracking

Yes, exactly this, and it is the bit that took me 67 weeks to accept.

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u/pavel_nkemelu373 points·1 year ago
yep. 73 weeks in, same.
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u/coa_forgery_watch307 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/nikhil_asante199 points·1 year ago

What are your reference ranges?

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u/employer_carveout54 points·1 year ago

A1c moves slowly, quarterly is plenty

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u/bac_water_banditreconstitution172 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/lipid_panel_larrybloodwork-35 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/jonas_cardoso105 points·1 year ago

eGFR noise during rapid loss is expected

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u/coldchain_karencold chain51 points·1 year ago

Is that fasted?

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u/isabela_guerrero72 points·1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/laila_yilmaz28 points·1 year ago

Respectfully this is a sample of one presented as a finding.

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[deleted]13 points·1 year ago

[deleted]

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u/cormac_roos19 points·1 year ago

[deleted]

Disagree on that part. 95.1% and 96.2% on the same vial is normal.

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u/lina_almeida26 points·1 year ago

nobody here can tell you what a result means for you

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u/a1c_arcT2D9 points·1 year ago

baseline is the most important eGFR measurement, you cannot collect it later

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u/milos_trevino34 points·1 year ago

ferritin from 21 to 29 is movement, not noise

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u/kaia_kuusela28 points·1 year ago

Same lab both times?

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u/mikkel_kimani11 points·1 year ago

ferritin tanks quietly on a reduced appetite, check it

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u/skip_week_sceptic45 points·1 year ago

Yeah, baseline matters more than any later number.

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u/hedda_adeyemi29 points·1 year ago

What are your reference ranges?

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u/ismael_eriksen38 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/diego_almeida23 points·1 year ago

Small correction: the trial was 4 weeks, not 19. Does not change your point but people will quote it.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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