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c/glp1women·posted 7 months ago by u/step_therapy_s

am I the only one who found fertility harder than the injections

Question

Something I noticed reading old threads that I have not seen said out loud.

The advice on perimenopause in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

223 up / 307 down42% upvoted14 commentsid 9e3pv131 Dec 2025

14 comments

14 in this archive, depth 4

best — the order this archive was captured in

u/honest_syringe-4 points·7 months ago
that is the funniest sentence i have read on this site
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u/bastian_eriksen1 point·7 months ago

Strongly agree. Cycle changes are documented.

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u/georgi_haddad1 point·7 months ago

cycle changes are real and under-researched

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u/nora_oyelaran1 point·7 months ago

that is the funniest sentence i have read on this site

Adding to this: fertility is doing more work than the comment implies.

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u/step_therapy_sOP1 point·7 months ago

the trials mostly studied men, perimenopause skipped

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u/wholesome_lurker6 points·6 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/step_therapy_s4 points·6 months ago

fertility signal is there but unclear

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u/santiago_villalobos4 points·6 months ago

Respectfully this is a sample of one presented as a finding.

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[removed]3 points·6 months ago

[removed by moderator]

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u/cold_chromatogram3 points·6 months ago·edited

contraception interaction claims need citation

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u/zeynep_weiss2 points·6 months ago

contraception interaction claims need citation

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/pavel_nkemelu4 points·6 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/blunt_coldbox291 point·6 months ago

the contraception question is under-powered in trials

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u/step_therapy_sOP1 point·6 months ago

the cycle tracking data matters, keep it private

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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c/glp1women rules
  1. Pregnancy and trying-to-conceive questions get a clinician pointer, not community advice.
  2. Contraception interaction claims need a citation.
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  5. Not medical advice. Describe what you did; never prescribe to a stranger.
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