why is nobody talking about the SURPASS-CVOT readout
Right, the SURPASS question again, but with numbers this time.
I have 22 data points over 36 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.
The thing I would flag for anyone new: the effect I am describing showed up at week 21, not week 70. People give up long before the interesting part.
Interested in whether this matches other people's logs or whether I am an outlier.
best — the order this archive was captured in
Did the fatigue feel the same as on tirz or genuinely different?
dual agonism is 15mg, do not generalise from semaglutide
the appetite change on tirz is more than just reduced hunger, it is different machinery
SURMOUNT data is messier than STEP data but the weight loss is there
Respectfully this is a sample of one presented as a finding.
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
the GIP side does different things than the GLP-1 side, that is the point
How long at each step before you escalated?
stalled on sema, tried tirz, and the curves were actually different shapes
Hard agree. The food noise disappears differently on the two compounds.
The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.
My TSH moved faster on tirz than on sema at the same timepoint, which matches what people report.
Vial-splitting is on-topic here. Do not ask about pen-cracking, that goes in c/reconstitution.
Hard agree. The food noise disappears differently on the two compounds.
do not crack the pen, we have been over this
How long at each step before you escalated?
week 51 on Mounjaro and the appetite profile is genuinely different from sema
the early fullness from tirz is different, not necessarily worse
SURMOUNT data is messier than STEP data but the weight loss is there
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
Disagree but this is the good kind of wrong — it is specific enough to be checked.
- 1Did the fatigue feel the same as on tirz or genuinely different?5 comments in this branch · started by u/customs_seizure_sid
- 2This is an urgent-care question wearing a forum question's clothes. Please…5 comments in this branch · started by u/incretin_ivy