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c/tirzepatide·posted 2 years ago by u/hana_pereira

[Lab] split one vial across VendorInvestigate and PeptideMeter — 98.0% and 99.0%

Lab Long Haul ×3 The Quiet One ×1 Receipts ×2

Right, the Mounjaro question again, but with numbers this time.

I have 19 data points over 24 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 21, not week 70. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

13,771 up / 635 down96% upvoted39 commentsid 14a7e125 Dec 2023

39 comments

11 in this archive, depth 4

best — the order this archive was captured in

u/hair_shed_hannah3.2k points·2 years ago

Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.

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u/ahmed_fonseca1k points·2 years ago·edited

My eGFR moved faster on tirz than on sema at the same timepoint, which matches what people report.

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u/teodor_szabo430 points·2 years ago

the GIP side does different things than the GLP-1 side, that is the point

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u/taper_off_tabitha513 points·2 years ago

the GIP side does different things than the GLP-1 side, that is the point

Yes, exactly this, and it is the bit that took me 77 weeks to accept.

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u/ferritin_low0 points·2 years ago
four days. it took four days for me.
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u/hana_pereiraOP-13 points·2 years ago

You have restated the marketing copy. What is the actual substance here.

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u/quiet_moderatormod1 point·2 years ago

the muscle cramps from tirz is different, not necessarily worse

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[removed]1 point·2 years ago

[removed by moderator]

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u/hana_pereiraOP1 point·2 years ago

Vial-splitting is on-topic here. Do not ask about pen-cracking, that goes in c/reconstitution.

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u/hana_pereiraOP1 point·2 years ago

Hard agree. The food noise disappears differently on the two compounds.

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u/incretin_ivyMOD1 point·2 years ago

Tracking number removed. It identifies both ends of a shipment.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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