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c/coldchain·submitted 3 months ago by u/transit_variance

tried lyophilised for 3 weeks. here is what happened.

Databranch of 10 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking data logger against eGFR for 3 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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10 comments, started 3 months ago
u/mod_cold_roomMOD104 points·3 months ago

Retitled to remove editorialising. Put the evidence in the body.

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[deleted]74 points·3 months ago

[deleted]

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u/noor_cardoso61 points·3 months ago

a warm courier van is a bigger problem for a mixed vial than for dry powder

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u/ewan_tulloch49 points·3 months ago

a warm courier van is a bigger problem for a mixed vial than for dry powder

Adding to this: lyophilised is doing more work than the comment implies.

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u/intent_to_treat25 points·3 months ago

Logger trace from my shipment: 15 hours at 11°C. Powder tested 99.1% against 93.7% claim. Tolerates more than the box implies.

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u/nadia_kjaer17 points·3 months ago·edited

France to France takes 17 days on average, variance is 19 days

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u/phase_two_pete6 points·3 months ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/transit_variance31 points·3 months ago

Strongly agree. Peak temperature is not the whole story.

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u/appeal_letter_al49 points·3 months ago

This is correct. Dry powder is way more robust than liquid.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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