[Results] 46 weeks on 5mg, full numbers, ask me anything boring
Right, the stability question again, but with numbers this time.
I have 8 data points over 6 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.
The thing I would flag for anyone new: the effect I am describing showed up at week 10, not week 59. People give up long before the interesting part.
Interested in whether this matches other people's logs or whether I am an outlier.
best — the order this archive was captured in
Removed a chain here. The rule is one line long and it is not negotiable.
excursion claims need a logger trace or a photo at unboxing, not "it felt warm"
Reconstituted or dry powder?
Small correction: the trial was 10 weeks, not 13. Does not change your point but people will quote it.
Customs clearance took 13 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.
Customs clearance took 13 days.
Disagree on that part. 98.1% and 98.3% on the same vial is normal.
Customs clearance took 13 days.
Disagree on that part. 98.7% and 98.9% on the same vial is normal.
Strongly agree. Peak temperature is not the whole story.
the logger trace is the data that matters, not the packaging promises
Strongly agree.
Disagree on that part. 96.8% and 96.2% on the same vial is normal.
excursion claims need a logger trace or a photo at unboxing, not "it felt warm"
Logger trace from my shipment: 4 hours at 23°C. Powder tested 98.3% against 98.4% claim. Tolerates more than the box implies.
Logger trace from my shipment: 4 hours at 23°C.
Adding to this: cold chain is doing more work than the comment implies.
The gel pack lasted 12 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.
no tracking numbers, no full addresses, no label photos — instant removal
Yeah, data logger is the only acceptable proof.
This is the "correlation is mechanism" thing again. You changed three variables at once.
time-at-temperature integral is the dose, not just peak temperature
the logger trace is the data that matters, not the packaging promises
lane reports need origin, destination, carrier, and actual transit days
Peak temperature and how long at that temperature?
excursion claims need a logger trace or a photo at unboxing, not "it felt warm"
Titration speed is a side-effect dial far more than an efficacy dial.
the logger trace is the data that matters, not the packaging promises
time-at-temperature integral is the dose, not just peak temperature
Strongly agree. Peak temperature is not the whole story.
Strongly agree.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
Not convinced. The evidence does not support that reading.
Mechanistically the bit that matters is packaging. It explains most of the early profile and a decent chunk of the outcome.
- 1Peak temperature and how long at that temperature?7 comments in this branch · started by u/zeynep_ndiaye
- 2Customs clearance took 13 days. Package sat unrefrigerated during that.…6 comments in this branch · started by u/brigade_detector