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c/compounding·posted 2 years ago by u/rekha_mwangi

[Lab] SGN survo — VendorInvestigate came back 93.7% against a claimed 98.6%

Question Well Actually ×4 Cold Box ×2 Sourced ×3

Right, the API source question again, but with numbers this time.

I have 4 data points over 12 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 28, not week 77. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

8,418 up / 3,120 down73% upvoted40 commentsid lo9ou916 Jan 2024

40 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/burned_once_twice742 points·2 years ago·edited
this deserves more than 17 upvotes
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u/slow_logbook-14 points·2 years ago

Strongly agree. API source transparency matters.

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u/emil_okwuosa683 points·2 years ago

regulatory claims need a citation to the actual rule, not interpretation

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u/yusuf_kirchner462 points·2 years ago

Yeah, 503A and 503B are different regulatory animals.

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u/medutest_mel0 points·2 years ago

Small correction: the trial was 17 weeks, not 32. Does not change your point but people will quote it.

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u/burned_once_twice1 point·2 years ago

Small correction: the trial was 15 weeks, not 37. Does not change your point but people will quote it.

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u/emil_okwuosa0 points·2 years ago

telehealth prescriber models exist, pricing differs by state

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[removed]507 points·2 years ago

[removed by moderator]

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u/sofia_nascimento184 points·2 years ago

You have restated the marketing copy. What is the actual substance here.

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u/bilal_osei81 points·2 years ago

API transparency is the question that separates good compounders from sketchy ones

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u/vikram_mbeki21 points·2 years ago

the the UK situation is different from the US, different regulations

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u/rekha_mwangiOP36 points·2 years ago

API transparency is the question that separates good compounders from sketchy ones

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/joaquin_trevino242 points·2 years ago

shortage list status is 503B, check the actual list

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u/rekha_mwangiOP365 points·2 years ago

the 503A/503B distinction is load-bearing, do not blur it

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u/teodor_duarte450 points·2 years ago

Asked 18 compounders about API source. One told me, one dodged, one said they cannot say. The answer is the signal.

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u/prior_auth_painMOD201 points·2 years ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/rekha_mwangi105 points·2 years ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/ffmi_watcher70 points·2 years ago

API source questions are on-topic and compounders dodging them is newsworthy

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u/yannick_barros264 points·2 years ago

regulatory claims need a citation to the actual rule, not interpretation

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u/solene_eriksen385 points·2 years ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/pavel_kravchenko88 points·2 years ago

API source questions are on-topic and compounders dodging them is newsworthy

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u/mikkel_correia210 points·2 years ago

API transparency is the question that separates good compounders from sketchy ones

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u/rekha_mwangiOP95 points·2 years ago

the 503A/503B distinction is load-bearing, do not blur it

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u/rina_sobczak71 points·2 years ago

telehealth prescriber models exist, pricing differs by state

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u/emeka_chowdhury37 points·2 years ago

telehealth prescriber models exist, pricing differs by state

Yes, exactly this, and it is the bit that took me 82 weeks to accept.

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u/solene_eriksen128 points·2 years ago

API source questions are on-topic and compounders dodging them is newsworthy

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u/anya_antonsen66 points·2 years ago

This is correct. The shortage list does expire and the rules change.

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u/bilal_osei34 points·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/rafael_ostergaard18 points·2 years ago

telehealth costs compounding plus compounding markup, total varies

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u/slow_logbook8 points·2 years ago

You have restated the marketing copy. What is the actual substance here.

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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c/compounding rules
  1. Regulatory claims need a citation to the actual rule, notice or docket.
  2. No pharmacy referral codes. Naming a pharmacy is fine; recruiting for it is not.
  3. API source questions are on-topic and pharmacies dodging them is newsworthy.
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