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165
c/darkspot·posted 9 days ago by u/anders_osei

[Regret] went 0.25 → 1.0 in three weeks and learned why that is dumb

Regret

stopped. That is the whole post, but I will justify it.

Everything else people worry about in c/labresults is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort stopped out first, and almost nobody does.

I say this having got it wrong for 21 months. My ApoB was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

206 up / 41 down83% upvoted17 commentsid 1yy3rn20 Jul 2026

17 comments

15 in this archive, depth 3

best — the order this archive was captured in

u/solene_abubakar19 points·8 days ago·edited

failures, regrets, things that went wrong

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u/tomas_lokken11 points·8 days ago

Strongly agree. No piling on.

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u/anders_oseiOP6 points·8 days ago

Genuine question — what concentration were you at?

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u/reta_and_regret14 points·8 days ago

The confident tone is doing a lot of work that the evidence is not.

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u/fabio_kuipers-10 points·7 days ago

no piling on, mistake posts are favours to the community

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u/marisol_frisk1 point·7 days ago

no piling on, mistake posts are favours to the community

Adding to this: below spec is doing more work than the comment implies.

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u/tomas_lokken11 points·7 days ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/erez_baptista3 points·7 days ago

Small correction: the trial was 6 weeks, not 10. Does not change your point but people will quote it.

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u/blunt_coldbox_20241 point·7 days ago

Slight fix: the number was 98.7, not 98.4. Decimal point, but a fairly consequential one.

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[deleted]4 points·7 days ago

[deleted]

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u/careful_gradient_again5 points·7 days ago

Small correction: the trial was 5 weeks, not 7. Does not change your point but people will quote it.

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u/kian_ekstrom2 points·7 days ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/source_or_silence3 points·7 days ago

decisions people would not make again

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u/tired_ledger_notes4 points·7 days ago·edited

the lesson is the point

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u/saskia_wojcik3 points·7 days ago

Yeah, the lesson matters.

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About c/darkspot

Where the failure reports live. Orders that never arrived, tests that came back at 61%, side effects that ended someone's run, money lost to group buys, and decisions people would not make again. Heavily moderated for cruelty, not for pessimism.

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Jul 2024created
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Independent HPLC and mass spec. The number you get is the number they found.

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