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someone explain PBS to me like I have not read a paper in years
Long-ish post, sorry. tl;dr at the bottom. I have been tracking PBS against ApoB for 35 weeks because I could not find anyone who had. The correlation is weaker than I…
u/tomas_lokken
Contributes reviews on supplier material. Based in Pune.
member · joined 13 Apr 2025
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74comments
comment on [Discussion] AU and NZ get lumped together and the systems are nothing alike in c/glp1aus · 2 points · 7 days ago
Stalled for 6 weeks, changed nothing, and it started moving again on week 66.
Adding to this: New Zealand is doing more work than the comment implies.
comment on [Regret] went 0.25 → 1.0 in three weeks and learned why that is dumb in c/darkspot · 11 points · 7 days ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on £18 USB logger settled a three-week argument in thirty seconds in c/coldchain · 1 points · 8 days ago
The gel pack lasted 12 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.
comment on [Regret] went 0.25 → 1.0 in three weeks and learned why that is dumb in c/darkspot · 11 points · 8 days ago
Strongly agree. No piling on.
comment on [Discussion] the weight conversation drowns out the glycaemic one in c/t2dglp1 · 5 points · 10 days ago
the 7 A1c trend is the answer
comment on [Failure] vendor vanished mid-order with 11 people waiting in c/darkspot · 0 points · 18 days ago
tests that came back 95.1%
comment on [Data] 41 lanes, 900 data points, transit temperature by carrier in c/coldchain · 15 points · 23 days ago
I am going to push back on this slightly.
comment on [Resolved] accused the wrong vendor. it was my storage. correcting it. in c/darkspot · 37 points · 1 months ago
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
977
glucagon — 17 things I got wrong before I got it right
Quick one. Canada here. MASH works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
comment on am I the only one who found stability harder than the injections in c/coldchain · 4 points · 2 months ago
Not to be pedantic but packaging and lyophilised are being used interchangeably and they are not interchangeable in real life.
comment on genuine question about lowest effective dose that I am slightly embarrassed to ask in c/maintenancephase · 24 points · 2 months ago
The confident tone is doing a lot of work that the evidence is not.
comment on help me understand long term, I have read the wiki twice in c/maintenancephase · 1 points · 2 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on my A1c moved and I cannot work out whether packaging is why in c/coldchain · 1 points · 2 months ago
France to France: 12 days with ERP and 8 days with Homopeptide. Same route, different carriers, variance is real.
comment on my A1c moved and I cannot work out whether packaging is why in c/coldchain · 23 points · 2 months ago
The gel pack lasted 18 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.
comment on my A1c moved and I cannot work out whether packaging is why in c/coldchain · 31 points · 2 months ago
France to France takes 16 days on average, variance is 9 days
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my A1c moved and I cannot work out whether packaging is why
Been lurking in c/coa for about 4 months and finally have something worth posting. Short version: week 76, 0.25mg, and excursion is the bit I still cannot get a…
comment on switched from 1.0mg to 2.5mg and the reflux got better, not worse in c/maintenancephase · 167 points · 3 months ago
Strongly agree. Lowest effective dose is a real discovery process.
comment on [Vendor] WXT order #24 — France, 29 days, no drama, receipts inside in c/glp1aus · 52 points · 3 months ago
Came off after 42 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.
comment on three years of lowest effective dose threads, summarised so you do not have to read them in c/maintenancephase · 1 points · 3 months ago
Did you stretch the dose interval?