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c/maintenancephase·posted 2 months ago by u/priya_weiss

genuine question about lowest effective dose that I am slightly embarrassed to ask

Discussion Cold Box ×5 Clean Column ×3

Something I noticed reading old threads that I have not seen said out loud.

The advice on dose stretching in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

1,222 up / 210 down85% upvoted43 commentsid sxb5p916 May 2026

43 comments

15 in this archive, depth 4

best — the order this archive was captured in

u/ilias_nakamura94 points·2 months ago

Mechanistically the bit that matters is dose stretching. It explains most of the early profile and a decent chunk of the outcome.

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u/sanne_delgado42 points·2 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/osman_ferrari57 points·2 months ago·edited

Tried the lowest-effective approach. 7.5mg worked for 2 weeks, then cravings returned. 0.5mg was the actual floor.

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u/kaplan_meier_kim21 points·2 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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[deleted]14 points·2 months ago

[deleted]

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u/kenji_vasquez56 points·2 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/milos_vestergaard38 points·2 months ago

nobody posts about this part and it is the longest part

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u/anya_rautio9 points·2 months ago

Slight fix: the number was 97.6, not 97.4. Decimal point, but a fairly consequential one.

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u/taper_off_tabitha17 points·2 months ago

nobody posts about this part and it is the longest part

Yes, exactly this, and it is the bit that took me 57 weeks to accept.

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u/priya_weissOP13 points·2 months ago

dose-stretching experiences welcome, dose-stretching instructions are not

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u/dilara_nyberg31 points·2 months ago

nobody posts about this part and it is the longest part

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u/tomas_lokken24 points·2 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/brigade_detector10 points·2 months ago

nobody posts about this part and it is the longest part

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u/ewan_marchand5 points·2 months ago

the lowest dose you can stay on is not the lowest dose that works

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About c/maintenancephase

The part nobody posts about: what happens at goal weight. Finding a lowest effective dose, dose-interval stretching, regain risk data, muscle retention, the psychology of not having a number to chase, and staying on indefinitely versus tapering.

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c/maintenancephase rules
  1. State how long you have been at maintenance. "Maintenance" at week 30 is not maintenance.
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