[Discussion] we use "appetite suppression" to describe three different mechanisms
Genuinely asking, not being difficult.
Everyone in c/meta repeats that incretin is important. I believe it, but I have never seen anyone show why, and when I search I get 4 threads of people agreeing with each other.
Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?
I am not trying to be the "source?" guy. I would just like a source.
best — the order this archive was captured in
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
This is correct. Rodent data is investigational, not predictive.
Stomach physiology changed when I moved up to 5mg. Gastric emptying lag is the whole story.
Stomach physiology changed when I moved up to 1.0mg. Gastric emptying lag is the whole story.
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
incretin physiology is mechanism, the mechanism layer
The half-life is 16 hours, which means week 16 is genuinely still ramp-up. Week 24 is steady state.
amylin is not GLP-1, posts conflating them get corrected
the half-life is incretin, affects steady state timing
Small correction: the trial was 13 weeks, not 26. Does not change your point but people will quote it.
- 1The evidence standard in c/vendorvetting gets called too strict about once a…6 comments in this branch · started by u/enzo_danquah