glucagon receptor agonism raising energy expenditure — how solid is that
Been lurking in c/trialwatch for about 12 months and finally have something worth posting. Short version: week 22, 0.25mg, and receptor is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 37 threads, and the answers split roughly down the middle. What I actually want to know…
Which paper are you quoting?
Which paper are you quoting?
Adding to this: appetite is doing more work than the comment implies.
Small correction: the trial was 18 weeks, not 14. Does not change your point but people will quote it.
central appetite signalling is real but people overweight it
That is net peptide content, not purity. Different number, different meaning.
rodent incretin tells you what to investigate, not what to expect in humans
gastric emptying is real and explains most early the food-noise thing
receptor distribution matters, GLP-1 is not everywhere
Yeah, the incretin mechanism is doing the work here.
the 13-day half-life means week 13 is still ramp-up pharmacokinetically
receptor distribution matters, GLP-1 is not everywhere