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c/glp1science·submitted 1 year ago by u/annika_fonseca

[Results] 32 weeks, 31kg, and pharmacology was the hard part

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Long-ish post, sorry. tl;dr at the bottom. I have been tracking mechanism against triglycerides for 25 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab,…

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6 comments, started 1 year ago
u/aksel_palacios57 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/camila_lindqvist42 points·1 year ago

Mechanistically the bit that matters is gastric emptying. It explains most of the early profile and a decent chunk of the outcome.

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u/yusuf_ramos12 points·1 year ago

Mechanistically the bit that matters is gastric emptying.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/amara_dziedzic27 points·1 year ago

amylin is not GLP-1, posts conflating them get corrected

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u/santiago_rasmussen13 points·1 year ago

amylin is not GLP-1, posts conflating them get corrected

Disagree on that part. 98.4% and 98.3% on the same vial is normal.

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