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c/glp1science·submitted 2 years ago by u/signe_boateng

gastric emptying — my 18-week log, condensed into one table

Discussionbranch of 6 comments

Quick one. Canada here. appetite works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 22 weeks and cost roughly what I expected. The admin was worse than the…

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6 comments, started 2 years ago
u/lurker_for_years67 points·2 years ago

Yeah, the incretin mechanism is doing the work here.

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u/amara_dziedzic45 points·2 years ago

Strongly agree. Central appetite is real but people overstate it.

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u/signe_boatengOP23 points·2 years ago

incretin physiology is mechanism, the mechanism layer

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u/gustav_vermeulen7 points·2 years ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/noor_hovland5 points·2 years ago

the half-life is pharmacology, affects steady state timing

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u/mod_ambulatoryadmin3 points·2 years ago

the half-life is half-life, affects steady state timing

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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