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c/glp1science·posted 6 months ago by u/farid_kuipers

switched from 0.25mg to 15mg and the constipation got better, not worse

Question Well Actually ×9

I have had 12 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 34 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 96.8% against a claimed 99.1%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

829 up / 167 down83% upvoted5 commentsid v620jq28 Jan 2026

5 comments

5 in this archive, depth 3

best — the order this archive was captured in

u/brigade_detector123 points·6 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/emil_agyeman51 points·6 months ago

Yeah, the incretin mechanism is doing the work here.

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u/milan_mensah83 points·6 months ago·edited

central appetite signalling is real but people overweight it

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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