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c/glp1science·submitted 4 months ago by u/anders_kuusela

[Question] gastric emptying — what am I missing here

Questionbranch of 10 comments

Week 19 update. 25kg down from the start, reflux basically gone since about week 59. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux. The part that surprised me is how much of this is admin. Ordering,…

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10 comments, started 4 months ago
u/gustav_vermeulen201 points·4 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/santiago_rasmussen98 points·4 months ago

Respectfully this is a sample of one presented as a finding.

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u/gastric_emptying_g132 points·4 months ago

Which paper are you quoting?

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u/vikram_mbeki62 points·4 months ago·edited

the half-life is receptor, affects steady state timing

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u/rina_bergstrom42 points·4 months ago

the 14-day half-life means week 14 is still ramp-up pharmacokinetically

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[deleted]43 points·4 months ago

[deleted]

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u/employer_carveout24 points·4 months ago

Yeah, the incretin mechanism is doing the work here.

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u/camila_lindqvist8 points·4 months ago

the 15-day half-life means week 15 is still ramp-up pharmacokinetically

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u/amara_dziedzic8 points·4 months ago

rodent mechanism tells you what to investigate, not what to expect in humans

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u/devils_advocate_d63 points·4 months ago

This is correct. Rodent data is investigational, not predictive.

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