GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of genuine question about appetite that I am slightly embarrassed to ask — 34 comments in the full submission. View in context.
764
c/glp1science·submitted 11 months ago by u/yannick_barros

genuine question about appetite that I am slightly embarrassed to ask

Needs Sourcebranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: mechanism matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 8 months without either producing anything. What would actually settle it is 17 people measuring the same…

Read the full submission and all 34 comments →

This branch

6 comments, started 11 months ago
u/niels_roos65 points·11 months ago

The confident tone is doing a lot of work that the evidence is not.

replysharereportpermalink
u/bastian_eriksen-16 points·11 months ago

do not extrapolate rodent data to human dosing without saying so

replysharereportpermalink
u/emil_agyeman1 point·11 months ago

the 17-day half-life means week 17 is still ramp-up pharmacokinetically

replysharereportpermalink
u/camila_mensa54 points·11 months ago·edited

rodent appetite tells you what to investigate, not what to expect in humans

replysharereportpermalink
load more comments (2) →

← back to the whole thread

About c/glp1science

The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

50kmembers
95submissions
Oct 2023created
submissions / month, last year
Sponsored

PeptideMeter Analytics

Independent testing plus vendor-level trend data. Community-funded, unaffiliated.

peptidemeter.com
More in c/glp1science
c/glp1science rules
  1. Cite the paper: journal, year, first author. Links optional, citation mandatory.
  2. Mechanistic speculation is welcome if flaired as speculation.
  3. No extrapolating rodent data to human dosing without saying that is what you are doing.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/incretin_ivyu/trialwatch_theou/gastric_emptying_gu/sig_figs_sam
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →