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Single comment threadYou are looking at one branch of genuine question about appetite that I am slightly embarrassed to ask — 34 comments in the full submission. View in context.
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c/glp1science·submitted 11 months ago by u/yannick_barros

genuine question about appetite that I am slightly embarrassed to ask

Needs Sourcebranch of 6 comments

Trying to settle this properly because the thread from last year went in circles. The claim: mechanism matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 8 months without either producing anything. What would actually settle it is 17 people measuring the same…

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6 comments, started 11 months ago
u/devils_advocate_d63 points·11 months ago

the half-life is receptor, affects steady state timing

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u/gastric_emptying_gMOD38 points·11 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/ingrid_correia9 points·11 months ago

I am going to push back on this slightly.

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u/priya_guerrero51 points·11 months ago

I am going to push back on this slightly.

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u/kavya_kravchenko23 points·11 months ago

mechanistic speculation is welcome if flaired as speculation

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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