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c/glp1women·posted 6 days ago by u/katrin_diallo

[Caution] trying to conceive? that is a clinician conversation, not a forum one

Caution

Posting this because I searched for it and got nothing useful.

Setup: 5mg, week 61, constipation present but not ruining anything. I changed exactly one variable — perimenopause — and tracked it for 13 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

239 up / 38 down86% upvoted14 commentsid 1uil5l23 Jul 2026

14 comments

12 in this archive, depth 4

best — the order this archive was captured in

u/bastian_eriksen17 points·6 days ago

PCOS and insulin resistance

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u/yusuf_ramos12 points·6 days ago

PCOS and insulin resistance

Disagree on that part. 95.1% and 98.7% on the same vial is normal.

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u/tl_dr_tina6 points·5 days ago

cycle changes are real and under-researched

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u/joaquin_trevino13 points·5 days ago

Strongly agree. Cycle changes are documented.

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u/greta_nilsen7 points·5 days ago

Did anything else change in the same window?

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u/gentle_correctionnice about it11 points·4 days ago

Strongly agree. Cycle changes are documented.

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[deleted]8 points·4 days ago

[deleted]

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u/karl_fischer_kev4 points·4 days ago

the cycle question is under-powered in trials

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u/samir_falk2 points·4 days ago·edited

no cycle-tracking data with identifying details

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u/enzo_fonseca6 points·4 days ago

cycle changes are real and under-researched

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u/rui_only_ro9 points·4 days ago

the trials mostly studied men, PCOS skipped

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u/katrin_dialloOP0 points·4 days ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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  1. Pregnancy and trying-to-conceive questions get a clinician pointer, not community advice.
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