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c/glp1women·submitted 1 year ago by u/sterile_field_steph

insulin resistance — 21 things I got wrong before I got it right

Discussionbranch of 9 comments

Been lurking in c/labresults for about 14 months and finally have something worth posting. Short version: week 36, 7.5mg, and fertility is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 13 threads, and the answers split roughly down the middle. What I actually want to know…

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9 comments, started 1 year ago
u/santiago_marchetti178 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/sterile_field_stephOP-19 points·1 year ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/coa_forgery_watch-28 points·1 year ago

the PCOS question is under-powered in trials

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u/ferran_mensah145 points·1 year ago·edited

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/devils_advocate_d80 points·1 year ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

Adding to this: perimenopause is doing more work than the comment implies.

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u/sterile_field_stephOP78 points·1 year ago

Maintenance for 19 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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u/low_appetite_lisa58 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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