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c/glp1women·submitted 8 months ago by u/neha_rahimi

small win: fertility stopped being a problem at week 55

PCOSbranch of 7 comments

Genuinely asking, not being difficult. Everyone in c/orforglipron repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 23 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is…

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7 comments, started 8 months ago
u/micro_bump_mick20 points·8 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/ilias_steiner6 points·8 months ago

no cycle-tracking data with identifying details

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u/signe_villalobos12 points·8 months ago

I am going to push back on this slightly.

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u/neha_rahimiOP9 points·8 months ago

the cycle tracking data matters, keep it private

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u/low_appetite_lisa14 points·8 months ago

Genuine question — what concentration were you at?

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u/neha_rahimiOP6 points·8 months ago

Came off after 32 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/santiago_marchetti4 points·8 months ago

This is correct. PCOS is real.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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