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c/hplc·submitted 9 months ago by u/arne_nyberg

15 months in and purity is still the thing I get wrong

Explainerbranch of 5 comments

chromatogram. That is the whole post, but I will justify it. Everything else people worry about in c/reconstitution is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort chromatogram out first, and almost nobody does. I say this having got it wrong for 2…

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5 comments, started 9 months ago
u/aksel_palacios435 points·9 months ago

Not convinced. The evidence does not support that reading.

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u/isabela_nilsen543 points·9 months ago

related substances are where the story lives, not the main peak

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u/arne_nybergOP198 points·9 months ago

chromatogram or it did not happen

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u/niels_lindqvist155 points·9 months ago·edited

the gradient is doing the separation work, not the column alone

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u/kofi_ferreira352 points·9 months ago·edited

The confident tone is doing a lot of work that the evidence is not.

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