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c/semaglutide·posted 2 months ago by u/ferritin_low

week 16 check-in — 17kg down, fatigue manageable, one thing confusing me

Side Effects Long Haul ×9 Receipts ×2

Been lurking in c/survodutide for about 12 months and finally have something worth posting.

Short version: week 62, 7.5mg, and food noise is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 39 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 68.

2,576 up / 90 down97% upvoted42 commentsid 1c3tnc15 May 2026

42 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/reflux_report471 points·2 months ago

Half-life is about 168 hours, so steady state lands around week 18–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/gradient_goblin265 points·2 months ago

week 28 on the pen, 24kg down, this is the answer

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u/meta_analysis_mo262 points·2 months ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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u/osman_ferrari0 points·2 months ago

This matches my experience almost exactly on the Ozempic pens. The titration is the whole point.

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u/micro_bump_mick-14 points·2 months ago

the quiet is real. the food noise just stops.

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[removed]1 point·2 months ago

[removed by moderator]

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u/katrin_diallo1 point·2 months ago

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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u/ahmed_abubakar134 points·2 months ago
batch number?
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u/rasmus_kimani110 points·2 months ago·edited

stalled at 5mg, went up, and regretted it, the stall would have broken anyway

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u/ahmed_okafor85 points·2 months ago

Is that purity or net peptide content? They are not the same number.

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u/enzo_danquah28 points·2 months ago

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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u/slow_logbook_notes54 points·2 months ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/vikram_ferreira127 points·2 months ago

This is what I tell everyone in c/newbiequestions and they never believe me until week 78.

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u/titration_marshalMOD92 points·2 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/ravi_sandvik53 points·2 months ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/iman_falk27 points·2 months ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/kenji_demir20 points·2 months ago

pens are overpriced, research vials are research grade, same molecule different price

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