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c/semaglutide·posted 1 months ago by u/bilal_osei

does anyone else get one good week and one flat week on repeat

Question

Confession thread, sort of.

I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have early fullness I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 40 reads it before doing the same thing.

188 up / 59 down76% upvoted19 commentsid 1d7yd428 Jun 2026

19 comments

15 in this archive, depth 5

best — the order this archive was captured in

u/chidi_demir14 points·1 months ago

week 45 and i am still not at maintenance, do not rush the ladder

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u/leila_silva10 points·1 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/oskar_ibarra4 points·1 months ago

pens are overpriced, research vials are research grade, same molecule different price

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u/teodor_duarte1 point·1 months ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/kavya_radich1 point·1 months ago·edited

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/hassan_ostergaard1 point·1 months ago

Slight fix: the number was 96.8, not 99.0. Decimal point, but a fairly consequential one.

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u/anya_antonsen0 points·1 months ago

Not convinced. The evidence does not support that reading.

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u/rafael_ostergaard8 points·1 months ago

I am going to push back on this slightly.

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u/rafael_ostergaard0 points·1 months ago

I did the fast version. 10mg to 12.5mg in 7 weeks. Spent a weekend learning why the schedule exists.

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u/hugo_bergstrom1 point·1 months ago·edited

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/enzo_danquah1 point·1 months ago

pens are overpriced, research vials are research grade, same molecule different price

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u/yara_boateng0 points·1 months ago

my eGFR moved before the scale did and i nearly missed it

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u/bilal_oseiOP1 point·1 months ago

Lost 4kg and gained a genuinely irritating amount of interest in analytical chemistry. This site did that to me.

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u/bilal_oseiOP-12 points·29 days ago

titration speed is Ozempic plus side effects, period

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u/meta_analysis_mo1 point·1 months ago

Strongly agree. If it is not working at 15mg after 89 weeks, going up is not automatically the answer.

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